WIDESPREAD RECOMBINATION, REASSORTMENT, AND TRANSMISSION OF UNBALANCED COMPOUND VIRAL GENOTYPES IN NATURAL ARENAVIRUS INFECTIONS.

Widespread recombination, reassortment, and transmission of unbalanced compound viral genotypes in natural arenavirus infections.

Arenaviruses are one of the largest families of human hemorrhagic fever viruses and are known to infect both mammals and snakes.Arenaviruses package a large (L) and small (S) genome segment in their virions.For segmented RNA viruses like these, novel genotypes can be generated through mutation, recombination, and reassortment.Although it is believe

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Biomedical and pharmacological potential of tetrodotoxin-producing bacteria isolated from marine pufferfish Arothron hispidus (Muller, 1841)

Specimens of the pufferfish Arothron hispidus collected at Parangipettai, on the southeast coast of India, were subjected to bacterial isolation and identification.Three species were identified, namely Bacillus sp., Kytococcus sedentarius and Cellulomonas fimi.Partially-purified microbial Game Bird Supplements filtrates exhibited hemolytic activity

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Curcumin Delivery Mediated by Bio-Based Nanoparticles: A Review

Todays, nano-pharmaceutics is emerging as an important field of science to develop and improve efficacy of different drugs.Although Masthead Amplifier Power Injector nutraceuticals are currently being utilized in the prevention and treatment of various chronic diseases such as cancers, a number of them have displayed issues associated with their so

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Associations of filaggrin gene loss-of-function variants and human papillomavirus-related cancer and pre-cancer in Danish adults.

Filaggrin proteins are expressed in the skin, oral cavity, oesophagus, and cervical mucose.Loss-of-function mutations in the filaggrin gene (FLG) reduce filaggrin expression and cause an impaired skin barrier function.We hypothesized that FLG mutation carriers would be more susceptible to human papillomavirus (HPV) infection and thus a higher risk

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